منابع مشابه
The Gap Junction Communication Channel
Communication plays an important role in the rapid Connexin Structure progress of modern society. We live in an age when Gap junctions exhibit a hierarchy of assembly. The prininformation is transmitted through many different pathcipal structural component, the membrane protein conways and in many different forms to influence our daily nexin, is organized into the basic unit of structure, the d...
متن کاملAssembly of gap junction intercellular communication channels.
788 with a lipidlprotein molar ratio of 100:1, a value close to that found in most biological membranes [21]. The data show that the calculation of distances between sites within the monomer of a membrane protein of a cross-sectional diameter of 5 nm based only from FET efficiency measurements is largely speculative in most cases in native biological membranes. Because the contribution of FET t...
متن کاملGap junction communication channel: peptides and anti-peptide antibodies as structural probes.
856 benzodiazepine photoaffinity labelling site on the GABA, receptor a 1 subunit [ 121. Further, it should be pointed out that an alternative approach to synthetic peptides as antigens for directed antibody production is the use of bacterially produced subunit fragments, and indeed this strategy has been adopted for the GAHA, receptor [13]. In general these antigens, although probably less exp...
متن کاملMonovalent Cation Permeation through the Connexin40 Gap Junction Channel
The unitary conductances and permeability sequences of the rat connexin40 (rCx40) gap junction channels to seven monovalent cations and anions were studied in rCx40-transfected neuroblastoma 2A (N2A) cell pairs using the dual whole cell recording technique. Chloride salt cation substitutions (115 mM principal salt) resulted in the following junctional maximal single channel current-voltage rela...
متن کاملGap junction-mediated intercellular communication in the immune system.
Immune cells are usually considered non-attached blood cells, which would exclude the formation of gap junctions. This is a misconception since many immune cells express connexin 43 (Cx43) and other connexins and are often residing in tissue. The role of gap junctions is largely ignored by immunologists as is the immune system in the field of gap junction research. Here, the current knowledge o...
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ژورنال
عنوان ژورنال: Cell
سال: 1996
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(00)81282-9